Composition : Levetiracetam 500mg

Form : Tablets / Pack : 10X10’s / Type : Blister

Description : Levetiracetam is a novel antiepileptic drug (AED) with favorable pharmacologic characteristics and demonstrated activity in improving seizure control. Three multicenter double-blind, placebo-controlled studies were conducted in 904 patients with refractory partial-onset seizures. Patients were required to have a minimum of two or four seizures per week (depending on the study) and were maintained on a stable regimen of one or two AEDs at baseline that was continued during the study period. Patients ranged in age from 14 to 70 years, with a mean age of approximately 37 years. After an 8- to 12-week baseline period, patients were randomized and had doses titrated upward every 2 weeks over a period of 4 weeks to a target dose of 1,000, 2,000, or 3,000 mg/day of levetiracetam or placebo. Treatment was continued for a 12- to 14-week evaluation phase followed by an optional open-label treatment phase. Levetiracetam was generally well tolerated in all studies. Results from these three pivotal studies demonstrate that levetiracetam, as adjunctive therapy, is a safe and effective treatment for refractory partial-onset seizures in adults - Epilepsia . 2001; 42 Suppl 4:31-5.

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Levetiracetam 500mg

Composition : Pregabalin 75mg+ Methycobalamin1500mcg+ Nortriptyline10mg

Form : Tablets / Pack : 1 X 10's / Type : AA

Description : Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin helps in the production of myelin, that protects nerve fibers and rejuvenates damaged nerve cells. Altogether, they relieve neuropathic pain.

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Methycobalamin1500mcg Nortriptyline10mg Pregabalin 75mg

Composition : Pregabalin 75mg + Methycobalamin 750mcg+Nortriptyline 10mg

Form : Tablet / Pack : 10 x 10s / Type : ALU-ALU

Description : A combination of three medicines- Pregabalin is an alpha 2 delta legend which decreases pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Together, they relieve neuropathic pain.

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Methylcobalamin Nortriptyline Pregablin

Composition : Nortriptyline 5mg + Gabapentin 200mg

Form : Tablets / Pack : 10 X 10 / Type : ALU-ALU

Description : Gabapentin reduces lesion-induced hyperexcitability of posterior horns neurons, which is responsible for central sensitization. It also decreases calcium entry into nerve endings and thus decreases release of neurotransmitters- BioMed Research International; volume 2014. Nortriptyline is a tricyclic antidepressant that is occasionally used for treating neuropathic pain and is recommended in Europe, UK, and USA guidelines- Derry S1 et al; Cochrane Database SystRev, 2015 Jan 8. The combination of Gabapentin plus Nortriptyline, reduces neruopathic pain more than either drug alone - Lancet 2009 Oct 10;374(9697):1252-61

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Gabapentin Nortriptyline

Composition : Nortriptyline 10mg.

Form : Tablets / Pack : 10 x 10's / Type : ALU-ALU

Description : Nortriptyline is the major active metabolite of amitriptyline, a first-generation TCA. It is the N-desmethyl metabolite of amitriptyline. Like amitriptyline it works by inhibiting the reuptake of serotonin and norepinephrine, thereby enhancing synaptic signalling via these neurotransmitters. It preferentially inhibits the reuptake of norepinephrine over serotonin, which is the opposite to amitriptyline.. In 2010, an evidence-based guideline sponsored by the International Association for the Study of Pain recommended nortriptyline as a first-line medication for neuropathic pain.

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Nortriptyline

Composition : Pregabelin 75mg + Methycobalamin 750mcg

Form : Capsules / Pack : 10's / Type : ALU-ALU

Description : Improves Nerves Conduction Velocity. Reduces Numbness & Muscles Cramp. Promotes Myelination in Neurons. Relieves Anxiolytic Effects.

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Methylcobalamin Pregablin

Composition : Citicholine 500mg & Piracetam 800mg

Form : Tablets / Pack : 10’S / Type : ALU-ALU

Description : Citicholine Readily passes into BBB directly into brain tissue. Levin HS, 1991; Shimamoto K & Azamaki J1975 Citicholine Supports Membrane integrity, Enhances Acetyl choline formation Contribute to critical metabolic functions (RNA & DNA). Cleark WM et al Shimamoto k Azamaki 1975 Piracetam Several Placebo controlled trails suggests that Piracetam is effective in recovery from Aphasia soon after Stoke Piracetam Improves Neuronal Efficiency

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Citicholine Piracetam

Composition : Nortriptyline 5mg + Gabapentin 200mg

Form : Tablets / Pack : 10’s / Type : ALU-ALU

Description : Gabapentin reduces lesion-induced hyperexcitability of posterior horns neurons, which is responsible for central sensitization. It also decreases calcium entry into nerve endings and thus decreases release of neurotransmitters. BioMed Research International; volume 2014 Nortriptyline is a tricyclic antidepressant that is occasionally used for treating neuropathic pain and is recommended in Europe, UK, and USA guidelines. Derry S1 et al; Cochrane Database SystRev, 2015 Jan 8 The combination of Gabapentin plus Nortriptyline, reduces neruopathic pain more than either drug alone - Lancet 2009 Oct 10;374(9697):1252-61

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Gabapentin Nortriptyline