Axodil Respules
The Algorithm Of Asthma Management

Composition : Levosalbutamol 0.63mg per Respule

/ Pack : 10 x 5 x 2.5ml / Type : Combipack Respules

Description : Activation of β2 adrenergic receptors on airway smooth muscle leads to the activation of adenylate cyclase and to an increase in the intracellular concentration of cyclic AMP resulting the activation of protein kinase A, which in turn, inhibits the phosphorylation of myosin and lowers intracellular ionic calcium concentrations, Hence causes muscle relaxation. Levosalbutamol being a functional short-acting β2 adrenergic receptor agonist, relaxes the smooth muscles from the trachea to the terminal bronchioles. Increased cyclic AMP concentrations are also associated with the inhibition of the release of mediators from mast cells in the airways, irrespective of the spasmogen involved, thereby protecting against all bronchoconstrictor challenges.

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